The average bus between Milan and Lyon takes 6h 33m and the fastest bus takes 6h 10m. The bus service runs several times per day from Milan to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Milan and Lyon. The earliest departure is at 5:45 AM in the morning, and the last departure from Milan is at 11:45 PM which arrives into Lyon at 6:30 AM. All services run direct with no transfers required, and take on average 6h 33m. The schedules shown below are for the next available departures.
Want to know about travelling from Milan to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Milan station and arriving at Lyon station. Services depart every 3 hours, and operate Twice daily. The journey takes approximately 6h 33m.
Milan to Lyon bus services, operated by FlixBus, depart from Milano, Autostazione Lampugnano station.
Milan to Lyon bus services, operated by FlixBus, arrive at Lyon station.
Book your Milan to Lyon bus tickets online with FlixBus.
The distance between Milan and Lyon is 339.3 km. The road distance is 443 km.
FlixBus operates a bus from Milano, Autostazione Lampugnano to Lyon every 3 hours. Tickets cost €29–55 and the journey takes 6h 10m. BlaBlaCar Bus also services this route 4 times a day.