The average bus between Milan and Alessano takes 22h 53m and the fastest bus takes 18h 17m. The bus service runs several times per day from Milan to Alessano. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Milan and Alessano. The earliest departure is at 8:15 AM in the morning, and the last departure from Milan is at 11:05 PM which arrives into Alessano at 5:22 PM. All services require a transfer at Lecce and take an average of 22h 53m. The schedules shown below are for the next available departures.
Arrives next day

26h 30m • 1 change
Arrives next day

19h 40m • 1 change
Arrives next day

26h 30m • 1 change
Arrives next day

18h 17m • 1 change
Arrives next day

26h 30m • 1 change
Arrives next day

18h 17m • 1 change
Want to know about travelling from Milan to Alessano? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Milan to Alessano. However, there are services departing from Milan station and arriving at Alessano station via Lecce. The journey, including transfers, takes approximately 22h 53m.
Milan to Alessano bus services, operated by FlixBus, depart from Milano, San Donato M3 station.
Milan to Alessano bus services, operated by FlixBus, arrive at Alessano station.
Book your Milan to Alessano bus tickets online with FlixBus, Salento in bus and Elios Autoservizi.
The distance between Milan and Alessano is 969.9 km. The road distance is 1,103 km.
You can take a bus from Milano, San Donato M3 to Alessano via Lecce and Lecce Via V. Carluccio in around 16h 6m.