The average bus between Middlesex and Boston takes 7h 6m and the fastest bus takes 6h 7m. There is a bus service every few hours from Middlesex to Boston. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Middlesex and Boston. The earliest departure is at 6:12 AM in the morning, and the last departure from Middlesex is at 10:30 PM which arrives into Boston at 5:30 AM. All services require a transfer, and take on average 7h 6m. The schedules shown below are for the next available departures.

7h 32m • 1 change

7h 32m • 1 change

7h 17m • 1 change

7h 52m • 1 change

6h 9m • 1 change

7h 18m • 1 change

7h 32m • 1 change

7h 32m • 1 change

6h 9m • 1 change

7h 18m • 1 change

7h 32m • 1 change

7h 32m • 1 change

6h 9m • 1 change

6h 39m • 1 change

7h 18m • 1 change

7h 32m • 1 change

6h 32m • 1 change

6h 9m • 1 change

6h 39m • 1 change

7h 18m • 1 change
Want to know about travelling from Middlesex to Boston? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Middlesex to Boston. However, there are services departing from Middlesex station and arriving at Boston station via Port Authority Bus Terminal. The journey, including transfers, takes approximately 7h 6m.
Middlesex to Boston bus services, operated by NJ Transit, depart from Boundbrook Rd At 4Th St station.
Middlesex to Boston bus services, operated by NJ Transit, arrive at South Station.
The distance between Middlesex and Boston is 348.2 km. The road distance is 484 km.
You can take a bus from Boundbrook Rd At 4Th St to South Station via Port Authority Bus Terminal in around 6h 55m.