Middlesex to Boston Buses

Middlesex to Boston buses

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Trip Overview

The average bus between Middlesex and Boston takes 7h 37m and the fastest bus takes 6h 4m. There is a bus service every few hours from Middlesex to Boston. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

7h 37m
Duration: 300 mi
Distance: $67
Average price: Hourly
Frequency

Bus

best

Take the bus from Boundbrook Rd At 4Th St to Port Authority Bus Terminalbus 114
Take the bus from New York to Bostonbus Ppb 5623 / ...

7h 16m

$52–109

Middlesex to Boston bus times

Buses run hourly between Middlesex and Boston. The earliest departure is at 6:12 AM in the morning, and the last departure from Middlesex is at 10:41 PM which arrives into Boston at 11:30 AM. All services require a transfer at Port Authority Bus Terminal and take an average of 7h 37m. The schedules shown below are for the next available departures.

Departing Monday, October 26, 2026

1:17 PM → 8:45 PM
7h 27m • 1 change
3:18 PM → 10:50 PM
7h 31m • 1 change
7:13 PM → 1:35 AM
Arrives next day
6h 21m • 1 change
10:30 PM → 11:30 AM
Arrives next day
12h 59m • 1 change

Departing Tuesday, October 27, 2026

7:50 AM → 1:55 PM
6h 4m • 1 change
9:16 AM → 4:45 PM
7h 28m • 1 change
10:17 AM → 6:00 PM
7h 42m • 1 change
11:17 AM → 6:45 PM
7h 27m • 1 change
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Departing Wednesday, October 28, 2026

7:50 AM → 1:55 PM
6h 4m • 1 change
9:16 AM → 4:45 PM
7h 28m • 1 change
10:17 AM → 6:00 PM
7h 42m • 1 change
11:17 AM → 6:45 PM
7h 27m • 1 change
Show more

Departing Thursday, October 29, 2026

7:50 AM → 1:55 PM
6h 4m • 1 change
8:25 AM → 3:05 PM
6h 39m • 1 change
9:16 AM → 4:45 PM
7h 28m • 1 change
10:17 AM → 6:00 PM
7h 42m • 1 change
Show more

Departing Friday, October 30, 2026

6:12 AM → 12:30 PM
6h 17m • 1 change
7:50 AM → 1:55 PM
6h 4m • 1 change
8:25 AM → 3:05 PM
6h 39m • 1 change
9:16 AM → 4:45 PM
7h 28m • 1 change
Show more

Departing Saturday, October 31, 2026

7:28 AM → 1:55 PM
6h 27m • 1 change
8:28 AM → 3:05 PM
6h 37m • 1 change
9:10 AM → 4:45 PM
7h 34m • 1 change
10:14 AM → 6:00 PM
7h 45m • 1 change
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Departing Sunday, November 1, 2026

7:31 AM → 1:55 PM
6h 23m • 1 change
8:09 AM → 3:05 PM
6h 55m • 1 change
9:07 AM → 4:45 PM
7h 37m • 1 change
10:08 AM → 6:00 PM
7h 51m • 1 change
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Frequently asked questions

Want to know about travelling from Middlesex to Boston? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.