The average bus between Messina and Pienza takes 21h 17m and the fastest bus takes 18h 9m. The bus service runs several times per day from Messina to Pienza. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Messina and Pienza. The earliest departure is at 10:55 AM in the morning, and the last departure from Messina is at 8:15 PM which arrives into Pienza at 2:24 PM. All services require a transfer at Siena and take an average of 21h 17m. The schedules shown below are for the next available departures.
Arrives next day


21h 39m • 2 changes
Arrives next day


18h 9m • 2 changes
Arrives next day


21h 39m • 2 changes
Arrives next day


18h 9m • 2 changes
Want to know about travelling from Messina to Pienza? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Messina to Pienza. However, there are services departing from Messina station and arriving at Pienza station via Siena. The journey, including transfers, takes approximately 21h 17m.
Messina to Pienza bus services, operated by FlixBus, depart from Messina station.
Messina to Pienza bus services, operated by FlixBus, arrive at Siena station.
The distance between Messina and Pienza is 633.5 km. The road distance is 965 km.
FlixBus operates a bus from Messina to Siena twice daily. Tickets cost €70–120 and the journey takes 11h 30m. Itabus S.p.A. also services this route once daily.