Rome2Rio

Mesa to Portland buses

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Trip Overview

The average bus between Mesa and Portland takes 45h 44m and the fastest bus takes 45h 33m. The bus runs, on average, 4 times per week from Mesa to Portland. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

45h 44m
Duration
1,467 mi
Distance
$298
Average price
4 times a week
Frequency

Mesa to Portland bus times

Buses run 4 times a week between Mesa and Portland. The earliest departure is at 11:51 AM in the morning, and the last departure from Mesa is at 12:12 PM which arrives into Portland at 8:45 AM. All services require a transfer at University Dr & Rural Rd and take an average of 45h 44m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

  •  → 

    Arrives +2 days

    Valley MetroFlixbus USAFlixbus USAGreyhound USAGreyhound USA45h 45m • 4 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives +2 days

    Valley MetroFlixbus USAFlixbus USAGreyhound USAGreyhound USA45h 45m • 4 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives +2 days

    Valley MetroFlixbus USAFlixbus USAGreyhound USAGreyhound USA45h 54m • 4 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives +2 days

    Valley MetroFlixbus USAFlixbus USAGreyhound USAGreyhound USA45h 33m • 4 changes

Frequently asked questions

Want to know about travelling from Mesa to Portland? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Mesa to Portland.ExpandLaunch map view
  • Distance: 1,467.2 mi
  • Duration: 45h 44m

What companies run services between Mesa, AZ, USA and Portland, OR, USA?

You can take a bus from University Dr & Mesa Dr to Portland Curbside Bus Stop via University Dr & Rural Rd, Tempe, Phoenix Sky Harbor Airport/44th Street Sky Train Station, Los Angeles Union Station, and Sacramento Bus Station in around 36h 48m.

Operators