The average bus between Medford and Santa Rosa takes 27h 15m and the fastest bus takes 26h 55m. There is at least one bus per day from Medford to Santa Rosa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Medford and Santa Rosa. The earliest departure is at 9:20 AM in the morning, and the last departure from Medford is at 12:20 PM which arrives into Santa Rosa at 3:15 PM. All services require a transfer at Crescent City Cultural Center/CoC and take an average of 27h 15m. The schedules shown below are for the next available departures.
Arrives next day


27h 35m • 2 changes
Arrives next day


26h 55m • 2 changes
Arrives next day


27h 35m • 2 changes
Arrives next day


26h 55m • 2 changes
Want to know about travelling from Medford to Santa Rosa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Medford to Santa Rosa. However, there are services departing from Medford station and arriving at Santa Rosa station via Crescent City Cultural Center/CoC. The journey, including transfers, takes approximately 27h 15m.
Medford to Santa Rosa bus services, operated by Point, depart from Front Street Station - Medford.
Medford to Santa Rosa bus services, operated by Point, arrive at Santa Rosa Amtrak Bus Stop station.
The distance between Medford and Santa Rosa is 432.3 km. The road distance is 716 km.
You can take a bus from Front Street Station - Medford to Santa Rosa Amtrak Bus Stop via Crescent City Cultural Center/CoC, Grocery Outlet, and Arcata in around 14h 1m.