The average bus between Massachusetts and Indiana takes 24h 5m and the fastest bus takes 21h. The bus service runs several times per day from Massachusetts to Indiana. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Massachusetts and Indiana. The earliest departure is at 1:30 AM at night, and the last departure from Massachusetts is at 5:15 PM which arrives into Indiana at 4:00 PM. All services require a transfer, and take on average 24h 5m. The schedules shown below are for the next available departures.
Arrives next day

25h 30m • 1 change
Arrives next day

22h 45m • 1 change
Arrives next day

25h 30m • 1 change
Arrives next day

22h 45m • 1 change
Arrives next day

25h 30m • 1 change
Arrives next day

22h 45m • 1 change
Want to know about travelling from Massachusetts to Indiana? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Massachusetts to Indiana. However, there are services departing from Massachusetts station and arriving at Indiana station via Newark Penn Station station. The journey, including transfers, takes approximately 24h 5m.
Massachusetts to Indiana bus services, operated by Greyhound USA, depart from Boston station.
Massachusetts to Indiana bus services, operated by Greyhound USA, arrive at Indianapolis station.
Book your Massachusetts to Indiana bus tickets online with Greyhound USA and Flixbus USA.
The distance between Massachusetts and Indiana is 1,200.8 km. The road distance is 1,569 km.
You can take a bus from Boston to Indianapolis via Newark Penn Station in around 21h 20m.