The average bus between Massachusetts and Indiana takes 23h 44m and the fastest bus takes 21h 40m. The bus service runs several times per day from Massachusetts to Indiana. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Massachusetts and Indiana. The earliest departure is at 2:15 AM at night, and the last departure from Massachusetts is at 8:30 PM which arrives into Indiana at 6:10 PM. All services require a transfer, and take on average 23h 44m. The schedules shown below are for the next available departures.
Arrives next day

25h 55m • 1 change
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23h 20m • 1 change
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21h 40m • 1 change
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22h 40m • 1 change
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23h 20m • 1 change
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21h 40m • 1 change
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25h 55m • 1 change
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23h 20m • 1 change
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21h 40m • 1 change
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25h 55m • 1 change
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23h 20m • 1 change
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22h 35m • 1 change
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25h 55m • 1 change
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23h 20m • 1 change
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22h 35m • 1 change
Want to know about travelling from Massachusetts to Indiana? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Massachusetts to Indiana. However, there are services departing from Massachusetts station and arriving at Indiana station via Port Authority Bus Terminal. The journey, including transfers, takes approximately 23h 44m.
Massachusetts to Indiana bus services, operated by Greyhound USA, depart from South Station.
Massachusetts to Indiana bus services, operated by Greyhound USA, arrive at Indianapolis Union Station.
Book your Massachusetts to Indiana bus tickets online with Greyhound USA and Peter Pan Bus Lines.
The distance between Massachusetts and Indiana is 1,200.8 km. The road distance is 1,641 km.
You can take a bus from South Station to Indianapolis Union Station via Port Authority Bus Terminal in around 22h 40m.