The average bus between Manta and Cuenca takes 7h 17m and the fastest bus takes 6h 50m. There is a bus service every few hours from Manta to Cuenca. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Manta and Cuenca. The earliest departure is at 1:30 AM at night, and the last departure from Manta is at 9:30 PM which arrives into Cuenca at 5:00 AM. All services require a transfer, and take on average 7h 17m. The schedules shown below are for the next available departures.

7h 5m • 1 change

7h 15m • 1 change

6h 50m • 1 change

7h • 1 change

7h 15m • 1 change

6h 50m • 1 change

7h • 1 change

7h 10m • 1 change

7h 15m • 1 change

6h 50m • 1 change

7h • 1 change

7h 10m • 1 change
Want to know about travelling from Manta to Cuenca? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manta to Cuenca. However, there are services departing from Manta station and arriving at Cuenca station via Terminal Terrestre de Guayaquil. The journey, including transfers, takes approximately 7h 17m.
Manta to Cuenca bus services, operated by Reina del Camino, depart from Manta station.
Manta to Cuenca bus services, operated by Reina del Camino, arrive at Cuenca station.
The distance between Manta and Cuenca is 287.2 km. The road distance is 409 km.
You can take a bus from Manta to Cuenca via Terminal Terrestre de Guayaquil in around 6h 52m.