The average bus between Manhattan and Cape Cod and Islands takes 6h 42m and the fastest bus takes 6h 25m. The bus service runs several times per day from Manhattan to Cape Cod and Islands. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Manhattan and Cape Cod and Islands. The earliest departure is at 3:00 AM at night, and the last departure from Manhattan is at 2:30 PM which arrives into Cape Cod and Islands at 9:35 PM. All services require a transfer at Boston and take an average of 6h 42m. The schedules shown below are for the next available departures.

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Want to know about travelling from Manhattan to Cape Cod and Islands? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manhattan to Cape Cod and Islands. However, there are services departing from Manhattan station and arriving at Cape Cod and Islands station via Boston. The journey, including transfers, takes approximately 6h 42m.
Manhattan to Cape Cod and Islands bus services, operated by Flixbus USA, depart from New York Midtown station.
Manhattan to Cape Cod and Islands bus services, operated by Flixbus USA, arrive at Hyannis Transportation Center station.
The distance between Manhattan and Cape Cod and Islands is 316.7 km. The road distance is 457 km.
You can take a bus from New York Midtown to Hyannis Transportation Center via Boston and Boston South Station in around 6h 55m.