The average bus between Manchester and Thame takes 7h 6m and the fastest bus takes 5h 10m. The bus service runs several times per day from Manchester to Thame. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Manchester and Thame. The earliest departure is at 5:15 AM in the morning, and the last departure from Manchester is at 7:30 PM which arrives into Thame at 7:00 AM. All services require a transfer at Milton Keynes Coachway and take an average of 7h 6m. The schedules shown below are for the next available departures.


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6h 36m • 2 changes


5h 28m • 2 changes


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6h 26m • 2 changes


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6h 26m • 2 changes


6h 8m • 2 changes


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6h 15m • 2 changes
Want to know about travelling from Manchester to Thame? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manchester to Thame. However, there are services departing from Manchester station and arriving at Thame station via Milton Keynes Coachway. The journey, including transfers, takes approximately 7h 6m.
Manchester to Thame bus services, operated by National Express, depart from Manchester Central Coach Station.
Manchester to Thame bus services, operated by National Express, arrive at Gloucester Green Bus Station.
The distance between Manchester and Thame is 210.6 km. The road distance is 329 km.
You can take a bus from Manchester Central Coach Station to Town Hall via Milton Keynes Coachway, Gloucester Green Bus Station, and High Street in around 7h 2m.