The average bus between Manchester and Southall takes 5h 53m and the fastest bus takes 5h 19m. The bus service runs several times per day from Manchester to Southall. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Manchester and Southall. The earliest departure is at 4:50 AM at night, and the last departure from Manchester is at 11:59 PM which arrives into Southall at 6:00 AM. All services require a transfer at London Heathrow Airport and take an average of 5h 53m. The schedules shown below are for the next available departures.

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Want to know about travelling from Manchester to Southall? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manchester to Southall. However, there are services departing from Manchester station and arriving at Southall station via London Heathrow Airport. The journey, including transfers, takes approximately 5h 53m.
Manchester to Southall bus services, operated by FlixBus, depart from Manchester, Shudehill Interchange station.
Manchester to Southall bus services, operated by FlixBus, arrive at London Heathrow Airport station.
The distance between Manchester and Southall is 253 km. The road distance is 330 km.
FlixBus operates a bus from Manchester, Shudehill Interchange to London Heathrow Airport every 4 hours. Tickets cost £19–35 and the journey takes 5h.