The average bus between Manchester and Piccadilly takes 5h 22m and the fastest bus takes 4h 29m. There is a bus service every few hours from Manchester to Piccadilly. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Manchester and Piccadilly. The earliest departure is at 2:45 AM at night, and the last departure from Manchester is at 3:50 PM which arrives into Piccadilly at 8:52 PM. All services require a transfer at Marble Arch and take an average of 5h 22m. The schedules shown below are for the next available departures.

5h 8m • 1 change

5h 46m • 1 change

6h 7m • 1 change

5h 18m • 1 change

5h 47m • 1 change

4h 40m • 1 change

5h 25m • 1 change

4h 47m • 1 change

5h 39m • 1 change

4h 49m • 1 change

5h 22m • 1 change

4h 45m • 1 change

5h 54m • 1 change

5h 5m • 1 change

6h • 1 change

5h 6m • 1 change
Want to know about travelling from Manchester to Piccadilly? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manchester to Piccadilly. However, there are services departing from Manchester station and arriving at Piccadilly station via Marble Arch. The journey, including transfers, takes approximately 5h 22m.
Manchester to Piccadilly bus services, operated by National Express, depart from Manchester Central Coach Station.
Manchester to Piccadilly bus services, operated by National Express, arrive at Marble Arch station.
The distance between Manchester and Piccadilly is 261.3 km. The road distance is 325 km.
National Express operates a bus from Manchester Central Coach Station to Marble Arch every 30 minutes. Tickets cost £35–90 and the journey takes 5h 40m.