The bus between Mainz and Brindisi takes 33h 30m. The bus runs, on average, 6 times per week from Mainz to Brindisi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 6 times a week between Mainz and Brindisi. The earliest departure is at 5:10 AM in the morning, and the last departure from Mainz is at 5:10 AM which arrives into Brindisi at 4:40 PM. All services require a transfer at Frankfurt central train station and take an average of 33h 30m. The schedules shown below are for the next available departures.
Want to know about travelling from Mainz to Brindisi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Mainz to Brindisi. However, there are services departing from Mainz station and arriving at Brindisi station via Bari. The journey, including transfers, takes approximately 33h 30m.
Mainz to Brindisi bus services, operated by FlixBus, depart from Frankfurt central train station.
Mainz to Brindisi bus services, operated by FlixBus, arrive at Brindisi station.
Book your Mainz to Brindisi bus tickets online with FlixBus.
The distance between Mainz and Brindisi is 1,282.9 km. The road distance is 1,830 km.
You can take a bus from Mainz central train station to Brindisi via Frankfurt central train station and Bari in around 28h 35m.
