The average bus between Lyon and Rome Termini takes 15h 16m and the fastest bus takes 14h 34m. The bus service runs several times per day from Lyon to Rome Termini. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Lyon and Rome Termini. The earliest departure is at 1:15 AM at night, and the last departure from Lyon is at 3:30 PM which arrives into Rome Termini at 7:29 AM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 15h 16m. The schedules shown below are for the next available departures.

15h 4m • 1 changeArrives next day

14h 34m • 1 changeArrives next day

15h 59m • 1 change
15h 15m • 1 change
15h 4m • 1 changeArrives next day

14h 54m • 1 changeArrives next day

15h 59m • 1 change
15h 15m • 1 change
15h 4m • 1 changeArrives next day

14h 54m • 1 changeArrives next day

15h 59m • 1 change
15h 15m • 1 change
15h 4m • 1 changeArrives next day

14h 39m • 1 changeArrives next day

16h 1m • 1 change
15h 20m • 1 change
15h 7m • 1 changeArrives next day

14h 41m • 1 changeArrives next day

15h 56m • 1 changeWant to know about travelling from Lyon to Rome Termini? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lyon to Rome Termini. However, there are services departing from Lyon station and arriving at Rome Termini station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 15h 16m.
Lyon to Rome Termini bus services, operated by BlaBlaCar Bus, depart from Gare de Lyon-Perrache station.
Lyon to Rome Termini bus services, operated by BlaBlaCar Bus, arrive at Roma, Autostazione Tiburtina station.
The distance between Lyon and Rome Termini is 747.7 km. The road distance is 1,034 km.
Itabus S.p.A. operates a bus from Gare de Lyon-Perrache to Roma, Autostazione Tiburtina twice daily. Tickets cost €60–130 and the journey takes 14h 30m. Two other operators also service this route.