The average bus between Lyon and Mendrisio takes 12h 56m and the fastest bus takes 9h 29m. The bus service runs several times per day from Lyon to Mendrisio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Lyon and Mendrisio. The earliest departure is at 12:05 AM at night, and the last departure from Lyon is at 12:45 PM which arrives into Mendrisio at 7:22 AM. All services require a transfer at Milan and take an average of 12h 56m. The schedules shown below are for the next available departures.
Want to know about travelling from Lyon to Mendrisio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lyon to Mendrisio. However, there are services departing from Lyon station and arriving at Mendrisio station via Milano, Autostazione Lampugnano. The journey, including transfers, takes approximately 12h 56m.
Lyon to Mendrisio bus services, operated by FlixBus, depart from Lyon - Gerland Bus Station.
Lyon to Mendrisio bus services, operated by FlixBus, arrive at Como station.
The distance between Lyon and Mendrisio is 321.2 km. The road distance is 501 km.
You can take a bus from Lyon - Gerland Bus Station to Mendrisio, Autosilo via Milan, Como, Como - San Rocchetto, and Chiasso, Stazione in around 9h 23m.