The average bus between Lyon and Istres takes 7h 32m and the fastest bus takes 5h 40m. The bus service runs several times per day from Lyon to Istres. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Lyon and Istres. The earliest departure is at 12:30 AM at night, and the last departure from Lyon is at 2:10 PM which arrives into Istres at 7:50 PM. All services require a transfer at Aix-en-Provence - Krypton Park & Ride and take an average of 7h 32m. The schedules shown below are for the next available departures.


6h 35m • 2 changes


5h 50m • 2 changes


6h 30m • 2 changes


6h 15m • 2 changes


6h 48m • 2 changes


6h 23m • 2 changes
Arrives next day


18h 2m • 2 changes


6h 39m • 2 changes


6h 15m • 2 changes


6h 35m • 2 changes


6h 53m • 2 changes
Want to know about travelling from Lyon to Istres? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lyon to Istres. However, there are services departing from Lyon station and arriving at Istres station via Aix-en-Provence - Krypton Park & Ride. The journey, including transfers, takes approximately 7h 32m.
Lyon to Istres bus services, operated by FlixBus, depart from Lyon - Gerland Bus Station.
Lyon to Istres bus services, operated by FlixBus, arrive at Aix-en-Provence - Krypton Park & Ride station.
The distance between Lyon and Istres is 248.8 km. The road distance is 358 km.
BlaBlaCar Bus operates a bus from Lyon - Gerland Bus Station to Aix-en-Provence - Krypton Park & Ride every 4 hours. Tickets cost €22–40 and the journey takes 3h 35m. FlixBus also services this route 4 times a day.