The average bus between Lyon and Isernia takes 19h 59m and the fastest bus takes 17h 25m. The bus service runs several times per day from Lyon to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Lyon and Isernia. The earliest departure is at 1:15 AM at night, and the last departure from Lyon is at 3:30 PM which arrives into Isernia at 1:25 PM. All services require a transfer, and take on average 19h 59m. The schedules shown below are for the next available departures.
Want to know about travelling from Lyon to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lyon to Isernia. However, there are services departing from Lyon station and arriving at Isernia station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 19h 59m.
Lyon to Isernia bus services, operated by Itabus S.p.A., depart from Lyon - Gerland Bus Station.
Lyon to Isernia bus services, operated by Itabus S.p.A., arrive at Isernia station.
Book your Lyon to Isernia bus tickets online with Itabus S.p.A., ATM Azienda di Trasporti Molisana S.p.A. and 2 other operators.
The distance between Lyon and Isernia is 884.1 km. The road distance is 1,184 km.
You can take a bus from Lyon - Gerland Bus Station to Isernia via Roma, Autostazione Tiburtina in around 17h 50m.
