Bus Lyon to Heidelberg from €53 | Tickets & Timetables

Trip Overview

The average bus between Lyon and Heidelberg takes 10h 50m and the fastest bus takes 9h 29m. The bus service runs several times per day from Lyon to Heidelberg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

10h 50m
Duration: 619 km
Distance: €53
Average price: 5 times a day
Frequency

Bus

best

Take the bus from Lyon to Karlsruhe central train stationbus N1316 / ...
Take the bus from Karlsruhe central train station to Heidelberg Pre Waypointbus FlixBus 108 / ...

9h 13m

€43–81

Lyon to Heidelberg bus times

Buses run 5 times a day between Lyon and Heidelberg. The earliest departure is at 2:05 AM at night, and the last departure from Lyon is at 10:00 PM which arrives into Heidelberg at 5:29 AM. All services require a transfer, and take on average 10h 50m. The schedules shown below are for the next available departures.

Departing Monday, April 27, 2026

5:05 PM → 1:54 AM
Arrives next day
8h 49m • 1 change
9:00 PM → 7:09 AM
Arrives next day
10h 9m • 1 change
10:00 PM → 5:29 AM
Arrives next day
7h 29m • 1 change

Departing Tuesday, April 28, 2026

3:20 AM → 11:04 AM
7h 44m • 1 change
5:20 AM → 12:49 PM
7h 29m • 1 change
5:30 AM → 8:29 PM
14h 59m • 1 change
5:05 PM → 1:54 AM
Arrives next day
8h 49m • 1 change
Show more

Departing Wednesday, April 29, 2026

5:20 AM → 12:49 PM
7h 29m • 1 change
5:30 AM → 8:29 PM
14h 59m • 1 change
5:05 PM → 1:54 AM
Arrives next day
8h 49m • 1 change
10:00 PM → 5:29 AM
Arrives next day
7h 29m • 1 change

Departing Thursday, April 30, 2026

2:05 AM → 9:39 AM
7h 34m • 1 change
5:20 AM → 12:49 PM
7h 29m • 1 change
5:30 AM → 8:29 PM
14h 59m • 1 change
5:05 PM → 1:54 AM
Arrives next day
8h 49m • 1 change
Show more

Departing Friday, May 1, 2026

5:20 AM → 12:49 PM
7h 29m • 1 change
5:30 AM → 8:29 PM
14h 59m • 1 change
5:05 PM → 1:54 AM
Arrives next day
8h 49m • 1 change
9:00 PM → 7:09 AM
Arrives next day
10h 9m • 1 change
Show more

Departing Saturday, May 2, 2026

2:05 AM → 9:39 AM
7h 34m • 1 change
3:20 AM → 11:04 AM
7h 44m • 1 change
5:20 AM → 12:49 PM
7h 29m • 1 change
5:30 AM → 8:29 PM
14h 59m • 1 change
Show more

Departing Sunday, May 3, 2026

3:20 AM → 11:04 AM
7h 44m • 1 change
5:20 AM → 12:49 PM
7h 29m • 1 change
5:30 AM → 8:29 PM
14h 59m • 1 change

Frequently asked questions

Want to know about travelling from Lyon to Heidelberg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.