The average bus between Luton and Slough takes 1h 50m and the fastest bus takes 1h 37m. There is a bus service every few hours from Luton to Slough. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Luton and Slough. The earliest departure is at 1:35 AM at night, and the last departure from Luton is at 6:45 PM which arrives into Slough at 8:23 PM. All services require a transfer, and take on average 1h 50m. The schedules shown below are for the next available departures.

1h 49m • 1 change

1h 50m • 1 change

1h 41m • 1 change

1h 46m • 1 change

1h 49m • 1 change

1h 49m • 1 change

1h 40m • 1 change

1h 45m • 1 change

1h 49m • 1 change

1h 49m • 1 change

1h 40m • 1 change

1h 45m • 1 change

1h 50m • 1 change

1h 50m • 1 change

2h 8m • 1 change

1h 53m • 1 change
Want to know about travelling from Luton to Slough? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Luton to Slough. However, there are services departing from Luton station and arriving at Slough station via Heathrow Central Bus Station station. The journey, including transfers, takes approximately 1h 50m.
Luton to Slough bus services, operated by National Express, depart from Luton Station Interchange.
Luton to Slough bus services, operated by National Express, arrive at Wellington Street Stop H station.
Book your Luton to Slough bus tickets online with National Express and First Berkshire & The Thames Valley.
The distance between Luton and Slough is 43 km. The road distance is 73 km.
You can take a bus from Luton Station Interchange to Wellington Street Stop H via Heathrow Central Bus Station in around 1h 35m.