The average bus between Luton and Middleton takes 5h 27m and the fastest bus takes 4h 28m. There is a bus service every few hours from Luton to Middleton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Luton and Middleton. The earliest departure is at 12:05 AM at night, and the last departure from Luton is at 10:45 PM which arrives into Middleton at 5:40 AM. All services require a transfer at Milton Keynes Coachway and take an average of 5h 27m. The schedules shown below are for the next available departures.


6h 47m • 2 changes


5h 29m • 2 changes


4h 55m • 2 changes


4h 56m • 2 changes


6h 47m • 2 changes


5h 29m • 2 changes


4h 55m • 2 changes


4h 56m • 2 changes


6h 47m • 2 changes


5h 29m • 2 changes


4h 55m • 2 changes


4h 56m • 2 changes


6h 47m • 2 changes


5h 29m • 2 changes


4h 55m • 2 changes


4h 56m • 2 changes
Want to know about travelling from Luton to Middleton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Luton to Middleton. However, there are services departing from Luton station and arriving at Middleton station via Manchester Central Coach Station station. The journey, including transfers, takes approximately 5h 27m.
Luton to Middleton bus services, operated by National Express, depart from Milton Keynes Coachway station.
Luton to Middleton bus services, operated by National Express, arrive at Manchester Central Coach Station.
The distance between Luton and Middleton is 221.1 km. The road distance is 288 km.
National Express operates a bus from Milton Keynes Coachway to Manchester Central Coach Station hourly. Tickets cost £29–70 and the journey takes 3h 55m.