The average bus between Luton and Isleworth takes 3h 3m and the fastest bus takes 1h 42m. The bus service runs several times per day from Luton to Isleworth. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Luton and Isleworth. The earliest departure is at 1:35 AM at night, and the last departure from Luton is at 6:45 PM which arrives into Isleworth at 12:18 AM. All services require a transfer, and take on average 3h 3m. The schedules shown below are for the next available departures.

1h 42m • 1 change

1h 46m • 1 change
Arrives next day

5h 35m • 1 change

1h 44m • 1 change

1h 49m • 1 change
Arrives next day

5h 33m • 1 change

1h 44m • 1 change

1h 49m • 1 change
Arrives next day

5h 33m • 1 change

1h 44m • 1 change

1h 49m • 1 change
Arrives next day

5h 33m • 1 change
Want to know about travelling from Luton to Isleworth? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Luton to Isleworth. However, there are services departing from Luton station and arriving at Isleworth station via Heathrow Central Bus Station station. The journey, including transfers, takes approximately 3h 3m.
Luton to Isleworth bus services, operated by National Express, depart from Luton Station Interchange.
Luton to Isleworth bus services, operated by National Express, arrive at West Thames College station.
The distance between Luton and Isleworth is 45.3 km. The road distance is 71 km.
You can take a bus from Luton Station Interchange to West Thames College via Heathrow Central Bus Station in around 1h 57m.