The average bus between Lugano and Pisa takes 8h 46m and the fastest bus takes 8h 5m. The bus service runs several times per day from Lugano to Pisa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Lugano and Pisa. The earliest departure is at 3:15 AM at night, and the last departure from Lugano is at 2:20 PM which arrives into Pisa at 12:50 AM. All services require a transfer, and take on average 8h 46m. The schedules shown below are for the next available departures.

10h 5m • 1 change

11h 45m • 1 change
Arrives next day

10h 30m • 1 change

10h 5m • 1 change

11h 45m • 1 change
Arrives next day

10h 30m • 1 change
Want to know about travelling from Lugano to Pisa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lugano to Pisa. However, there are services departing from Lugano station and arriving at Pisa station via Milan. The journey, including transfers, takes approximately 8h 46m.
Lugano to Pisa bus services, operated by FlixBus, depart from Lugano station.
Lugano to Pisa bus services, operated by FlixBus, arrive at Pisa station.
Book your Lugano to Pisa bus tickets online with FlixBus.
The distance between Lugano and Pisa is 280.1 km. The road distance is 396 km.
You can take a bus from Lugano to Pisa via Milano, Autostazione Lampugnano in around 7h 15m.