The average bus between Lugano and Genoa takes 4h 42m and the fastest bus takes 3h 55m. The bus service runs several times per day from Lugano to Genoa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Lugano and Genoa. The earliest departure is at 3:15 AM at night, and the last departure from Lugano is at 5:40 PM which arrives into Genoa at 11:50 PM. All services require a transfer, and take on average 4h 42m. The schedules shown below are for the next available departures.

7h 10m • 1 change

5h 55m • 1 change

7h 50m • 1 change

6h 10m • 1 change

7h 10m • 1 change

5h 55m • 1 change

7h 50m • 1 change

6h 10m • 1 change
Want to know about travelling from Lugano to Genoa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lugano to Genoa. However, there are services departing from Lugano station and arriving at Genoa station via Milan. The journey, including transfers, takes approximately 4h 42m.
Lugano to Genoa bus services, operated by FlixBus, depart from Lugano station.
Lugano to Genoa bus services, operated by FlixBus, arrive at Genoa station.
Book your Lugano to Genoa bus tickets online with FlixBus and BlaBlaCar Bus.
The distance between Lugano and Genoa is 178.5 km. The road distance is 218 km.
You can take a bus from Lugano to Genoa via Milano, Autostazione Lampugnano in around 4h 15m.