The average bus between Lucerne and Milan takes 4h 13m and the fastest bus takes 3h 46m. The bus service runs several times per day from Lucerne to Milan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Lucerne and Milan. The earliest departure is at 5:15 AM in the morning, and the last departure from Lucerne is at 11:30 PM which arrives into Milan at 6:28 AM. All services require a transfer at via omodeo via cechov and take an average of 4h 13m. The schedules shown below are for the next available departures.

5h 48m • 1 change

6h 7m • 1 change
Arrives next day

6h 48m • 1 change

5h 48m • 1 change

6h 7m • 1 change
Arrives next day

6h 58m • 1 change
Want to know about travelling from Lucerne to Milan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lucerne to Milan. However, there are services departing from Lucerne station and arriving at Milan station via Milan. The journey, including transfers, takes approximately 4h 13m.
Lucerne to Milan bus services, operated by FlixBus, depart from Luzern station.
Lucerne to Milan bus services, operated by FlixBus, arrive at Milan station.
Book your Lucerne to Milan bus tickets online with FlixBus, ATM and RegioJet.
The distance between Lucerne and Milan is 189 km. The road distance is 241 km.
FlixBus operates a bus from Luzern to Milan 3 times a day. Tickets cost €19–35 and the journey takes 3h 20m. RegioJet also services this route 3 times a week.