The average bus between Lucerne and Italy takes 14h 13m and the fastest bus takes 12h 44m. The bus service runs several times per day from Lucerne to Italy. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Lucerne and Italy. The earliest departure is at 5:15 AM in the morning, and the last departure from Lucerne is at 11:30 PM which arrives into Italy at 2:14 PM. All services require a transfer at Milano, Autostazione Lampugnano and take an average of 14h 13m. The schedules shown below are for the next available departures.
Arrives next day


18h 52m • 2 changes
Arrives next day


14h 49m • 2 changes
Arrives next day


18h 52m • 2 changes
Arrives next day


14h 49m • 2 changes


15h 40m • 2 changes
Arrives next day


18h 58m • 2 changes
Arrives next day


14h 44m • 2 changes
Want to know about travelling from Lucerne to Italy? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lucerne to Italy. However, there are services departing from Lucerne station and arriving at Italy station via Milan. The journey, including transfers, takes approximately 14h 13m.
Lucerne to Italy bus services, operated by FlixBus, depart from Luzern station.
Lucerne to Italy bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
The distance between Lucerne and Italy is 599.2 km. The road distance is 843 km.
You can take a bus from Luzern to Termini via Milano, Autostazione Lampugnano and Roma, Autostazione Tiburtina in around 12h 41m.