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Louisville to Florida buses

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Trip Overview

The average bus between Louisville and Florida takes 21h 9m and the fastest bus takes 19h 5m. The bus service runs several times per day from Louisville to Florida. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

21h 9m
Duration
805 mi
Distance
$167
Average price
Twice daily
Frequency

Louisville to Florida bus times

Buses run twice daily between Louisville and Florida. The earliest departure is at 7:25 AM in the morning, and the last departure from Louisville is at 6:30 PM which arrives into Florida at 1:35 PM. All services require a transfer at Nashville Bus Station and take an average of 21h 9m. The schedules shown below are for the next available departures.

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayGreyhound USAFlixbus USA23h 35m • 2 changes
  •  → 

    Arrives next day

    Amtrak ThruwayFlixbus USAFlixbus USA19h 5m • 2 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayGreyhound USAFlixbus USA23h 35m • 2 changes
  •  → 

    Arrives next day

    Amtrak ThruwayFlixbus USAFlixbus USA19h 5m • 2 changes

Departing Tuesday, November 17, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayGreyhound USAFlixbus USA23h 35m • 2 changes
  •  → 

    Arrives next day

    Amtrak ThruwayFlixbus USAFlixbus USA19h 5m • 2 changes

Departing Wednesday, November 18, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayGreyhound USAFlixbus USA23h 35m • 2 changes
  •  → 

    Arrives next day

    Amtrak ThruwayFlixbus USAFlixbus USA19h 5m • 2 changes

Departing Thursday, November 19, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayGreyhound USAFlixbus USA23h 35m • 2 changes
  •  → 

    Arrives next day

    Amtrak ThruwayFlixbus USAFlixbus USA19h 5m • 2 changes

Departing Friday, November 20, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayGreyhound USAFlixbus USA23h 35m • 2 changes
  •  → 

    Arrives next day

    Amtrak ThruwayFlixbus USAFlixbus USA19h 5m • 2 changes

Frequently asked questions

Want to know about travelling from Louisville to Florida? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Louisville to Florida.ExpandLaunch map view
  • Distance: 805.4 mi
  • Duration: 21h 9m

What companies run services between Louisville, KY, USA and Florida, USA?

You can take a bus from Louisville, KY to Jacksonville via Nashville Bus Station and Atlanta Bus Station in around 16h.

Operators