The average bus between Louisville and Del Rio takes 39h 30m and the fastest bus takes 37h. The bus service runs several times per day from Louisville to Del Rio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Louisville and Del Rio. The earliest departure is at 6:00 AM in the morning, and the last departure from Louisville is at 6:20 PM which arrives into Del Rio at 11:20 AM. All services require a transfer at Nashville Bus Station and take an average of 39h 30m. The schedules shown below are for the next available departures.
Arrives next day



36h • 3 changes
Arrives +2 days



41h • 3 changes
Arrives next day



36h • 3 changes
Arrives +2 days



41h • 3 changes
Want to know about travelling from Louisville to Del Rio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Louisville to Del Rio. However, there are services departing from Louisville station and arriving at Del Rio station via Nashville. The journey, including transfers, takes approximately 39h 30m.
Louisville to Del Rio bus services, operated by Amtrak Thruway, depart from Louisville, KY station.
Louisville to Del Rio bus services, operated by Amtrak Thruway, arrive at Del Rio station.
The distance between Louisville and Del Rio is 1,709 km. The road distance is 2,159 km.
You can take a bus from Louisville, KY to Del Rio via Nashville Bus Station, Dallas Bus Station, and San Antonio Bus Station in around 28h 10m.