The average bus between London and Middleton takes 5h 59m and the fastest bus takes 5h 7m. There is a bus service every few hours from London to Middleton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between London and Middleton. The earliest departure is at 7:00 AM in the morning, and the last departure from London is at 11:59 PM which arrives into Middleton at 6:37 AM. All services require a transfer at Manchester, Shudehill Interchange and take an average of 5h 59m. The schedules shown below are for the next available departures.

5h 32m • 1 change

5h 36m • 1 change

6h 15m • 1 change

5h 55m • 1 change

5h 42m • 1 change

5h 32m • 1 change

5h 36m • 1 change

6h 15m • 1 change

5h 42m • 1 change

5h 32m • 1 change

5h 36m • 1 change

6h 15m • 1 change

5h 42m • 1 change

5h 32m • 1 change

5h 36m • 1 change

6h 15m • 1 change
Want to know about travelling from London to Middleton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from London to Middleton. However, there are services departing from London station and arriving at Middleton station via Manchester, Shudehill Interchange. The journey, including transfers, takes approximately 5h 59m.
London to Middleton bus services, operated by FlixBus, depart from London Victoria station.
London to Middleton bus services, operated by FlixBus, arrive at Manchester, Shudehill Interchange station.
The distance between London and Middleton is 266.9 km. The road distance is 326 km.
FlixBus operates a bus from London Victoria to Manchester, Shudehill Interchange hourly. Tickets cost £19–35 and the journey takes 4h 50m.