The average bus between Little Neck and Buffalo takes 10h 25m and the fastest bus takes 9h 47m. The bus service runs several times per day from Little Neck to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Little Neck and Buffalo. The earliest departure is at 10:38 AM in the morning, and the last departure from Little Neck is at 9:37 PM which arrives into Buffalo at 8:45 AM. All services require a transfer at 6 Av/W 37 St and take an average of 10h 25m. The schedules shown below are for the next available departures.

9h 56m • 1 change
Arrives next day

10h 22m • 1 change
Arrives next day

9h 57m • 1 change
Arrives next day

9h 47m • 1 change
Want to know about travelling from Little Neck to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Little Neck to Buffalo. However, there are services departing from Little Neck station and arriving at Buffalo station via Buffalo. The journey, including transfers, takes approximately 10h 25m.
Little Neck to Buffalo bus services, operated by MTA Bus Company, depart from New York Midtown station.
Little Neck to Buffalo bus services, operated by MTA Bus Company, arrive at Buffalo station.
The distance between Little Neck and Buffalo is 487.3 km. The road distance is 709 km.
Flixbus USA operates a bus from New York Midtown to Buffalo every 3 hours. Tickets cost $50–90 and the journey takes 7h 55m.