The average bus between Lecce and Guidonia takes 9h 50m and the fastest bus takes 9h 18m. The bus service runs several times per day from Lecce to Guidonia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Lecce and Guidonia. The earliest departure is at 5:00 AM in the morning, and the last departure from Lecce is at 10:55 PM which arrives into Guidonia at 8:28 AM. All services require a transfer at Rome Tiburtina Largo Mazzoni and take an average of 9h 50m. The schedules shown below are for the next available departures.


9h 18m • 2 changes


9h 38m • 2 changes


10h 8m • 2 changes
Arrives next day


9h 33m • 2 changes


9h 58m • 2 changes


9h 38m • 2 changes


10h 8m • 2 changes
Arrives next day


9h 33m • 2 changes


9h 58m • 2 changes


9h 18m • 2 changes


9h 38m • 2 changes


10h 8m • 2 changes


9h 58m • 2 changes


9h 18m • 2 changes


9h 38m • 2 changes


10h 8m • 2 changes


9h 58m • 2 changes


9h 18m • 2 changes


9h 38m • 2 changes


10h 8m • 2 changes


10h 48m • 2 changes


9h 28m • 2 changes


10h 3m • 2 changes
Arrives next day


9h 58m • 2 changes
Want to know about travelling from Lecce to Guidonia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lecce to Guidonia. However, there are services departing from Lecce station and arriving at Guidonia station via Rome Tiburtina Largo Mazzoni. The journey, including transfers, takes approximately 9h 50m.
Lecce to Guidonia bus services, operated by FlixBus, depart from Lecce Central Bus Station.
Lecce to Guidonia bus services, operated by FlixBus, arrive at Rome Tiburtina Largo Mazzoni station.
Book your Lecce to Guidonia bus tickets online with FlixBus, ATAC S.p.A. Azienda per la mobilità and Cotral S.p.A..
The distance between Lecce and Guidonia is 491.3 km. The road distance is 607 km.
Itabus S.p.A. operates a bus from Lecce Central Bus Station to Rome Tiburtina Largo Mazzoni once daily. Tickets cost €35–80 and the journey takes 8h 30m.