The average bus between Lecce and Guidonia takes 10h 6m and the fastest bus takes 9h 28m. The bus service runs several times per day from Lecce to Guidonia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Lecce and Guidonia. The earliest departure is at 5:00 AM in the morning, and the last departure from Lecce is at 10:55 PM which arrives into Guidonia at 7:48 AM. All services require a transfer at Rome Tiburtina Largo Mazzoni and take an average of 10h 6m. The schedules shown below are for the next available departures.


10h 28m • 2 changes

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10h 6m • 2 changes

9h 43m • 2 changes

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10h 6m • 2 changes

9h 43m • 2 changes

10h 28m • 2 changes

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10h 20m • 2 changes

9h 43m • 2 changes

10h 28m • 2 changes

10h • 2 changes

10h 20m • 2 changesWant to know about travelling from Lecce to Guidonia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lecce to Guidonia. However, there are services departing from Lecce station and arriving at Guidonia station via Rome Tiburtina Largo Mazzoni. The journey, including transfers, takes approximately 10h 6m.
Lecce to Guidonia bus services, operated by FlixBus, depart from Lecce Central Bus Station.
Lecce to Guidonia bus services, operated by FlixBus, arrive at Rome Tiburtina Largo Mazzoni station.
Book your Lecce to Guidonia bus tickets online with FlixBus, ATAC S.p.A. Azienda per la mobilità and Cotral S.p.A..
The distance between Lecce and Guidonia is 491.3 km. The road distance is 607 km.
Itabus S.p.A. operates a bus from Lecce Central Bus Station to Rome Tiburtina Largo Mazzoni once daily. Tickets cost €30–55 and the journey takes 8h 30m.