Rome2Rio

Lazio to Madrid buses

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Trip Overview

The average bus between Lazio and Madrid takes 39h 3m and the fastest bus takes 33h 45m. There is at least one bus per day from Lazio to Madrid. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

39h 3m
Duration
2,022 km
Distance
€221
Average price
Once daily
Frequency

Lazio to Madrid bus times

Buses run once daily between Lazio and Madrid. The earliest departure is at 12:44 AM at night, and the last departure from Lazio is at 6:45 AM which arrives into Madrid at 9:30 AM. All services require a transfer at Rome Tiburtina Bus station and take an average of 39h 3m. The schedules shown below are for the next available departures.

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBusFlixBus33h 45m • 2 changes

Departing Tuesday, November 17, 2026

  •  → 

    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBusFlixBus33h 45m • 2 changes

Departing Wednesday, November 18, 2026

  •  → 

    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBusFlixBus33h 45m • 2 changes

Departing Thursday, November 19, 2026

  •  → 

    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBusFlixBus33h 45m • 2 changes

Departing Friday, November 20, 2026

  •  → 

    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBusFlixBus33h 45m • 2 changes
  •  → 

    Arrives +2 days

    Cotral S.p.A.FlixBusFlixBus2d 3h • 2 changes

Frequently asked questions

Want to know about travelling from Lazio to Madrid? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Lazio to Madrid.ExpandLaunch map view
  • Distance: 2,022 km
  • Duration: 39h 3m

What companies run services between Lazio, Italy and Madrid, Spain?

You can take a bus from Termini to Madrid via Rome Tiburtina Bus station and Genoa in around 29h 53m.

Operators