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Key Largo to Anna Maria Island buses

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Trip Overview

The average bus between Key Largo and Anna Maria Island takes 20h 40m and the fastest bus takes 19h 21m. The bus service runs several times per day from Key Largo to Anna Maria Island. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

20h 40m
Duration
333 mi
Distance
$61
Average price
Twice daily
Frequency

Key Largo to Anna Maria Island bus times

Buses run twice daily between Key Largo and Anna Maria Island. The earliest departure is at 12:55 PM in the afternoon, and the last departure from Key Largo is at 8:00 PM which arrives into Anna Maria Island at 3:21 PM. All services require a transfer at Miami Airport Station and take an average of 20h 40m. The schedules shown below are for the next available departures.

Departing Sunday, November 15, 2026

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    Arrives next day

    Greyhound USAFlixbus USASarasota County Area TransitSarasota County Area TransitManatee County Area Transit19h 26m • 4 changes
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    Arrives next day

    Greyhound USAFlixbus USASarasota County Area TransitSarasota County Area TransitManatee County Area Transit19h 21m • 4 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USASarasota County Area TransitSarasota County Area TransitManatee County Area Transit19h 26m • 4 changes
  •  → 

    Arrives next day

    Greyhound USAFlixbus USASarasota County Area TransitSarasota County Area TransitManatee County Area Transit19h 21m • 4 changes

Departing Tuesday, November 17, 2026

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    Arrives next day

    Greyhound USAFlixbus USASarasota County Area TransitSarasota County Area TransitManatee County Area Transit19h 21m • 4 changes

Departing Wednesday, November 18, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USASarasota County Area TransitSarasota County Area TransitManatee County Area Transit19h 26m • 4 changes
  •  → 

    Arrives next day

    Greyhound USAFlixbus USASarasota County Area TransitSarasota County Area TransitManatee County Area Transit19h 21m • 4 changes

Departing Thursday, November 19, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USASarasota County Area TransitSarasota County Area TransitManatee County Area Transit19h 26m • 4 changes
  •  → 

    Arrives next day

    Greyhound USAFlixbus USASarasota County Area TransitSarasota County Area TransitManatee County Area Transit19h 21m • 4 changes

Departing Friday, November 20, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USASarasota County Area TransitSarasota County Area TransitManatee County Area Transit19h 26m • 4 changes
  •  → 

    Arrives next day

    Greyhound USAFlixbus USASarasota County Area TransitSarasota County Area TransitManatee County Area Transit19h 21m • 4 changes

Frequently asked questions

Want to know about travelling from Key Largo to Anna Maria Island? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Key Largo to Anna Maria Island.ExpandLaunch map view
  • Distance: 333.2 mi
  • Duration: 20h 40m

What companies run services between Key Largo, FL, USA and Anna Maria Island, FL, USA?

You can take a bus from Key Largo Bus Stop to Gulf Dr/42Nd St via Miami Airport Station, Sarasota Cattlemen Transfer Center, Cattlemen Transit Station, Downtown Transfer Station, 13Th St W @ 6Th Ave W Ns, and Downtown Station in around 10h 12m.

Operators