The average bus between Keele and Southampton takes 6h 59m and the fastest bus takes 6h 25m. The bus service runs several times per day from Keele to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Keele and Southampton. The earliest departure is at 6:15 AM in the morning, and the last departure from Keele is at 3:25 PM which arrives into Southampton at 10:20 PM. All services require a transfer, and take on average 6h 59m. The schedules shown below are for the next available departures.

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Want to know about travelling from Keele to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Keele to Southampton. However, there are services departing from Keele station and arriving at Southampton station via London Victoria. The journey, including transfers, takes approximately 6h 59m.
Keele to Southampton bus services, operated by FlixBus, depart from M6 Keele Services Southbound station.
Keele to Southampton bus services, operated by FlixBus, arrive at Coach Station.
Book your Keele to Southampton bus tickets online with FlixBus and National Express.
The distance between Keele and Southampton is 241.2 km. The road distance is 384 km.
You can take a bus from M6 Keele Services Southbound to Coach Station via London Victoria in around 6h 42m.