The average bus between Karlsruhe and Simmern takes 4h 55m and the fastest bus takes 3h 40m. The bus service runs several times per day from Karlsruhe to Simmern. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Karlsruhe and Simmern. The earliest departure is at 1:15 AM at night, and the last departure from Karlsruhe is at 9:50 PM which arrives into Simmern at 3:35 AM. All services require a transfer, and take on average 4h 55m. The schedules shown below are for the next available departures.

6h 35m • 1 change

6h 5m • 1 change

3h 40m • 1 change

4h • 1 change

8h 20m • 1 change

6h 5m • 1 change

8h 45m • 1 change

6h 15m • 1 change

8h 20m • 1 change

6h 35m • 1 change

6h 20m • 1 change

9h 15m • 1 change

7h 50m • 1 change

4h 55m • 1 change

6h 35m • 1 change

7h 35m • 1 change

7h 35m • 1 change

7h 5m • 1 change

3h 40m • 1 change

4h 15m • 1 change

6h 5m • 1 change

6h 5m • 1 change

6h 35m • 1 change

3h 40m • 1 change

6h 5m • 1 change

4h 10m • 1 change

6h 50m • 1 change

3h 55m • 1 change
Want to know about travelling from Karlsruhe to Simmern? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Karlsruhe to Simmern. However, there are services departing from Karlsruhe station and arriving at Simmern station via Frankfurt Airport. The journey, including transfers, takes approximately 4h 55m.
Karlsruhe to Simmern bus services, operated by FlixBus, depart from Karlsruhe central train station.
Karlsruhe to Simmern bus services, operated by FlixBus, arrive at Simmern Holzbacher Str. station.
Book your Karlsruhe to Simmern bus tickets online with FlixBus, Bohr and BlaBlaCar Bus.
The distance between Karlsruhe and Simmern is 125.5 km. The road distance is 246 km.
You can take a bus from Karlsruhe central train station to Simmern Holzbacher Str. via Frankfurt Airport P36 in around 4h 10m.