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Ithaca to Indianapolis buses

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Trip Overview

The average bus between Ithaca and Indianapolis takes 26h 56m and the fastest bus takes 21h 55m. The bus runs, on average, 5 times per week from Ithaca to Indianapolis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

26h 56m
Duration
681 mi
Distance
$119
Average price
5 times a week
Frequency

Ithaca to Indianapolis bus times

Buses run 5 times a week between Ithaca and Indianapolis. The earliest departure is at 5:05 AM in the morning, and the last departure from Ithaca is at 2:15 PM which arrives into Indianapolis at 3:00 AM. All services require a transfer at Buffalo and take an average of 26h 56m. The schedules shown below are for the next available departures.

Departing Thursday, October 8, 2026

  •  → 

    Arrives +2 days

    Flixbus USAFlixbus USAFlixbus USA36h 45m • 2 changes

Departing Saturday, October 10, 2026

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    Arrives next day

    Flixbus USAFlixbus USAFlixbus USA21h 55m • 2 changes

Departing Sunday, October 11, 2026

  •  → 

    Arrives next day

    Flixbus USAFlixbus USAFlixbus USA21h 55m • 2 changes

Departing Monday, October 12, 2026

  •  → 

    Arrives next day

    Flixbus USAFlixbus USAFlixbus USA21h 55m • 2 changes

Departing Tuesday, October 13, 2026

  •  → 

    Arrives next day

    Flixbus USAFlixbus USAFlixbus USA32h 10m • 2 changes

Frequently asked questions

Want to know about travelling from Ithaca to Indianapolis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Ithaca to Indianapolis.ExpandLaunch map view
  • Distance: 680.9 mi
  • Duration: 26h 56m

What companies run services between Ithaca, NY, USA and Indianapolis, IN, USA?

You can take a bus from Ithaca to Indianapolis via Buffalo and Columbus in around 15h 45m.

Operators