Rome2Rio

Italy to Prague buses

Find Transport to Prague

View schedule

Trip Overview

The average bus between Italy and Prague takes 23h 1m and the fastest bus takes 20h 39m. The bus runs, on average, 3 times per week from Italy to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

23h 1m
Duration
1,429 km
Distance
Kč 2,707
Average price
3 times a week
Frequency

Italy to Prague bus times

Buses run 3 times a week between Italy and Prague. The earliest departure is at 5:35 AM in the morning, and the last departure from Italy is at 12:31 PM which arrives into Prague at 9:10 AM. All services require a transfer, and take on average 23h 1m. The schedules shown below are for the next available departures.

Departing Friday, October 16, 2026

  •  → 

    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàRegioJet27h 34m • 1 change

Departing Sunday, October 18, 2026

  •  → 

    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàRegioJet20h 39m • 1 change

Departing Wednesday, October 21, 2026

  •  → 

    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàRegioJet20h 50m • 1 change

Frequently asked questions

Want to know about travelling from Italy to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Italy to Prague.ExpandLaunch map view
  • Distance: 1,429.4 km
  • Duration: 23h 1m

What companies run services between Italy and Prague, Czechia?

RegioJet operates a bus from Rome Tiburtina Bus Station to Prague Florenc Central Bus Station 4 times a week. Tickets cost Kč 2,100–3,400 and the journey takes 20h 10m.

Operators