Rome2Rio

Italy to Czechia buses

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Trip Overview

The average bus between Italy and Czechia takes 24h 32m and the fastest bus takes 20h 50m. The bus runs, on average, 3 times per week from Italy to Czechia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

24h 32m
Duration
1,429 km
Distance
Kč 2,625
Average price
3 times a week
Frequency

Italy to Czechia bus times

Buses run 3 times a week between Italy and Czechia. The earliest departure is at 6:45 AM in the morning, and the last departure from Italy is at 12:20 PM which arrives into Czechia at 9:10 AM. All services require a transfer, and take on average 24h 32m. The schedules shown below are for the next available departures.

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    Cotral S.p.A.RegioJet26h 24m • 1 change

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàRegioJet20h 50m • 1 change

Departing Wednesday, November 18, 2026

  •  → 

    Arrives next day

    Cotral S.p.A.RegioJet26h 24m • 1 change

Frequently asked questions

Want to know about travelling from Italy to Czechia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Italy to Czechia.ExpandLaunch map view
  • Distance: 1,429.4 km
  • Duration: 24h 32m

What companies run services between Italy and Czechia?

RegioJet operates a bus from Rome Tiburtina Bus Station to Prague Florenc Central Bus Station 4 times a week. Tickets cost Kč 2,200–3,600 and the journey takes 20h 10m.

Operators