The bus between Isernia and Messina takes 10h 35m. There is at least one bus per day from Isernia to Messina. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Isernia and Messina. The earliest departure is at 6:05 PM in the evening, and the last departure from Isernia is at 6:05 PM which arrives into Messina at 4:40 AM. All services require a transfer at Caserta Terminal Bus and take an average of 10h 35m. The schedules shown below are for the next available departures.
Want to know about travelling from Isernia to Messina? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Isernia to Messina. However, there are services departing from Isernia station and arriving at Messina station via Caserta Terminal Bus. The journey, including transfers, takes approximately 10h 35m.
Isernia to Messina bus services, operated by FlixBus, depart from Isernia station.
Isernia to Messina bus services, operated by FlixBus, arrive at Messina Piazza della Repubblica station.
Book your Isernia to Messina bus tickets online with FlixBus and Autoservizi Salemi Srl.
The distance between Isernia and Messina is 394.7 km. The road distance is 565 km.
You can take a bus from Isernia to Messina Piazza della Repubblica via Caserta Terminal Bus and Caserta Viale Vittorio Veneto in around 8h 55m.