The average bus between Independence and Saint Charles takes 11h 12m and the fastest bus takes 7h 25m. The bus service runs several times per day from Independence to Saint Charles. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Independence and Saint Charles. The earliest departure is at 4:19 AM at night, and the last departure from Independence is at 7:19 PM which arrives into Saint Charles at 10:09 AM. All services require a transfer at East Village - Bay A and take an average of 11h 12m. The schedules shown below are for the next available departures.



9h 49m • 3 changes



7h 25m • 3 changes
Arrives next day



12h 30m • 3 changes



9h 49m • 3 changes



7h 25m • 3 changes
Arrives next day



12h 30m • 3 changes



9h 49m • 3 changes



7h 25m • 3 changes
Arrives next day



15h 29m • 3 changes
Arrives next day



14h 49m • 3 changes
Want to know about travelling from Independence to Saint Charles? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Independence to Saint Charles. However, there are services departing from Independence station and arriving at Saint Charles station via St Louis Bus Station station. The journey, including transfers, takes approximately 11h 12m.
Independence to Saint Charles bus services, operated by Ride KC, depart from Kansas City Bus Station.
Independence to Saint Charles bus services, operated by Ride KC, arrive at St Louis Bus Station.
The distance between Independence and Saint Charles is 342 km. The road distance is 453 km.
Greyhound USA operates a bus from Kansas City Bus Station to St Louis Bus Station 4 times a day. Tickets cost $40–80 and the journey takes 4h.