The average bus between Hyannis and Holyoke takes 5h 22m and the fastest bus takes 4h 13m. The bus service runs several times per day from Hyannis to Holyoke. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Hyannis and Holyoke. The earliest departure is at 5:00 AM in the morning, and the last departure from Hyannis is at 9:00 PM which arrives into Holyoke at 5:37 AM. All services require a transfer at Boston, Bus Terminal South Station and take an average of 5h 22m. The schedules shown below are for the next available departures.


4h 14m • 2 changes


5h 13m • 2 changes
Arrives next day


8h 37m • 2 changes


4h 14m • 2 changes


4h 44m • 2 changes


4h 44m • 2 changes


4h 14m • 2 changes


4h 14m • 2 changes


4h 44m • 2 changes


4h 44m • 2 changes


4h 14m • 2 changes


4h 14m • 2 changes


4h 44m • 2 changes


4h 44m • 2 changes


4h 14m • 2 changes


4h 13m • 2 changes


4h 43m • 2 changes


4h 43m • 2 changes


4h 13m • 2 changes


4h 14m • 2 changes


4h 44m • 2 changes


4h 44m • 2 changes


4h 14m • 2 changes


4h 14m • 2 changes


4h 44m • 2 changes


4h 44m • 2 changes


4h 44m • 2 changes
Want to know about travelling from Hyannis to Holyoke? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Hyannis to Holyoke. However, there are services departing from Hyannis station and arriving at Holyoke station via Boston South Buses. The journey, including transfers, takes approximately 5h 22m.
Hyannis to Holyoke bus services, operated by Plymouth & Brockton, depart from Hyannis Transportation Center station.
Hyannis to Holyoke bus services, operated by Plymouth & Brockton, arrive at Springfield Union Station.
The distance between Hyannis and Holyoke is 202.5 km. The road distance is 272 km.
You can take a bus from Hyannis Transportation Center to High / Cabot via Boston, Bus Terminal South Station, Boston, Springfield Union Station, and Union Station Bay 9 in around 4h 41m.