Rome2Rio

Hotel Pisa, Rome to Florence buses

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Trip Overview

The average bus between Hotel Pisa, Rome and Florence takes 4h 7m and the fastest bus takes 3h 44m. There is a bus service every few hours from Hotel Pisa, Rome to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 7m
Duration
280 km
Distance
€34
Average price
Hourly
Frequency

Hotel Pisa, Rome to Florence bus times

Buses run hourly between Hotel Pisa, Rome and Florence. The earliest departure is at 5:49 AM in the morning, and the last departure from Hotel Pisa, Rome is at 10:25 PM which arrives into Florence at 2:10 AM. All services require a transfer at Conte Verde/Manzoni and take an average of 4h 7m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 24m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 56m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 6m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 5m • 1 change
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Departing Wednesday, November 11, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 48m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 9m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 24m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 56m • 1 change
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Departing Thursday, November 12, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 24m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 48m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 9m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 24m • 1 change
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Departing Friday, November 13, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 24m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 48m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 9m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 24m • 1 change
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Departing Saturday, November 14, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 25m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 50m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 7m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 13m • 1 change
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Departing Sunday, November 15, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 25m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 10m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 30m • 1 change
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Departing Monday, November 16, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 24m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 48m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 9m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 24m • 1 change
  • Show more

Frequently asked questions

Want to know about travelling from Hotel Pisa, Rome to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Hotel Pisa, Rome to Florence.ExpandLaunch map view
  • Distance: 279.8 km
  • Duration: 4h 7m

What companies run services between Hotel Pisa, Rome, Italy and Florence, Italy?

FlixBus operates a bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Station hourly. Tickets cost €24–40 and the journey takes 3h 15m. Three other operators also service this route.

Operators