Hotel Pisa, Rome to Florence Buses

Hotel Pisa, Rome to Florence buses

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Trip Overview

The average bus between Hotel Pisa, Rome and Florence takes 4h 6m and the fastest bus takes 3h 44m. There is a bus service every few hours from Hotel Pisa, Rome to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 6m
Duration: 280 km
Distance: €32
Average price: Hourly
Frequency

Bus

best

Take the bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Stationbus 510 / ...

4h 4m

€16–44

Hotel Pisa, Rome to Florence bus times

Buses run hourly between Hotel Pisa, Rome and Florence. The earliest departure is at 5:50 AM in the morning, and the last departure from Hotel Pisa, Rome is at 10:16 PM which arrives into Florence at 2:10 AM. All services require a transfer at Conte Verde/Manzoni and take an average of 4h 6m. The schedules shown below are for the next available departures.

Departing Tuesday, October 20, 2026

5:41 PM → 10:45 PM
5h 3m • 1 change
6:59 PM → 11:20 PM
4h 20m • 1 change
8:19 PM → 12:50 AM
Arrives next day
4h 30m • 1 change
9:01 PM → 1:00 AM
Arrives next day
3h 58m • 1 change
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Departing Wednesday, October 21, 2026

7:21 AM → 11:10 AM
3h 48m • 1 change
7:35 AM → 11:45 AM
4h 9m • 1 change
8:05 AM → 12:15 PM
4h 9m • 1 change
8:47 AM → 12:45 PM
3h 57m • 1 change
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Departing Thursday, October 22, 2026

5:50 AM → 10:15 AM
4h 24m • 1 change
7:21 AM → 11:10 AM
3h 48m • 1 change
7:35 AM → 11:45 AM
4h 9m • 1 change
8:05 AM → 12:15 PM
4h 9m • 1 change
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Departing Friday, October 23, 2026

5:50 AM → 10:15 AM
4h 24m • 1 change
7:21 AM → 11:10 AM
3h 48m • 1 change
7:35 AM → 11:45 AM
4h 9m • 1 change
8:05 AM → 12:15 PM
4h 9m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Hotel Pisa, Rome to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.