The average bus between Holyoke and Milwaukee takes 32h 6m and the fastest bus takes 26h 38m. There is at least one bus per day from Holyoke to Milwaukee. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Holyoke and Milwaukee. The earliest departure is at 3:26 PM in the afternoon, and the last departure from Holyoke is at 7:56 PM which arrives into Milwaukee at 8:30 AM. All services require a transfer at Union Station Bay 9 and take an average of 32h 6m. The schedules shown below are for the next available departures.
Arrives next day



25h 38m • 3 changes
Arrives +2 days



36h 33m • 3 changes
Arrives next day



25h 38m • 3 changes
Arrives +2 days



36h 33m • 3 changes
Arrives next day



25h 38m • 3 changes
Arrives +2 days



36h 33m • 3 changes
Want to know about travelling from Holyoke to Milwaukee? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Holyoke to Milwaukee. However, there are services departing from Holyoke station and arriving at Milwaukee station via New York Midtown. The journey, including transfers, takes approximately 32h 6m.
Holyoke to Milwaukee bus services, operated by PVTA, depart from Springfield Union Station.
Holyoke to Milwaukee bus services, operated by PVTA, arrive at Milwaukee Intermodal Station.
The distance between Holyoke and Milwaukee is 1,252.8 km. The road distance is 1,811 km.
You can take a bus from Maple / Sargeant to Milwaukee Intermodal Station via Union Station Bay 9, Springfield Union Station, New York Midtown, and Chicago Bus Station in around 24h 46m.