The average bus between Heidelberg and Mainz takes 2h 1m and the fastest bus takes 1h 54m. The bus service runs several times per day from Heidelberg to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Heidelberg and Mainz. The earliest departure is at 6:45 AM in the morning, and the last departure from Heidelberg is at 7:30 PM which arrives into Mainz at 9:24 PM. All services require a transfer, and take on average 2h 1m. The schedules shown below are for the next available departures.

1h 54m • 1 change

1h 54m • 1 change

1h 54m • 1 change

1h 54m • 1 change

2h 9m • 1 change

1h 54m • 1 change

1h 54m • 1 change

1h 54m • 1 change

2h 9m • 1 change

1h 54m • 1 change

1h 54m • 1 change

1h 54m • 1 change

2h 9m • 1 change

1h 54m • 1 change

1h 54m • 1 change

1h 54m • 1 change
Want to know about travelling from Heidelberg to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Heidelberg to Mainz. However, there are services departing from Heidelberg station and arriving at Mainz station via Frankfurt. The journey, including transfers, takes approximately 2h 1m.
Heidelberg to Mainz bus services, operated by HEAG mobilo GmbH, depart from Heidelberg, Hilton Hotel station.
Heidelberg to Mainz bus services, operated by HEAG mobilo GmbH, arrive at Ginsheim-Gustavsburg-Gustavsburg Am Alten Fährhaus station.
Book your Heidelberg to Mainz bus tickets online with HEAG mobilo GmbH and DB Bus.
The distance between Heidelberg and Mainz is 70.6 km. The road distance is 108 km.
You can take a bus from Heidelberg, Hilton Hotel to Ginsheim-Gustavsburg-Gustavsburg Am Alten Fährhaus via Frankfurt in around 1h 55m.