The average bus between Harrow and Southampton takes 3h and the fastest bus takes 2h 27m. There is a bus service every few hours from Harrow to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Harrow and Southampton. The earliest departure is at 12:09 AM at night, and the last departure from Harrow is at 10:50 PM which arrives into Southampton at 1:30 AM. All services require a transfer, and take on average 3h. The schedules shown below are for the next available departures.

2h 56m • 1 change

2h 46m • 1 change
Arrives next day

2h 41m • 1 change
Arrives next day

2h 40m • 1 change

2h 51m • 1 change

3h 10m • 1 change

3h 15m • 1 change

3h 15m • 1 change

2h 51m • 1 change

2h 48m • 1 change

2h 54m • 1 change

2h 56m • 1 change

2h 51m • 1 change

2h 48m • 1 change

2h 54m • 1 change

2h 56m • 1 change
Want to know about travelling from Harrow to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Harrow to Southampton. However, there are services departing from Harrow station and arriving at Southampton station via Heathrow Central Bus Station station. The journey, including transfers, takes approximately 3h.
Harrow to Southampton bus services, operated by First Bus London, depart from Harrow Bus Station.
Harrow to Southampton bus services, operated by First Bus London, arrive at Coach Station.
The distance between Harrow and Southampton is 105.8 km. The road distance is 127 km.
You can take a bus from Harrow Bus Station to Coach Station via Heathrow Central Bus Station in around 2h 58m.