The average bus between Harlem and Hyannis takes 8h 3m and the fastest bus takes 7h 30m. The bus service runs several times per day from Harlem to Hyannis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Harlem and Hyannis. The earliest departure is at 12:27 AM at night, and the last departure from Harlem is at 5:49 PM which arrives into Hyannis at 1:35 AM. All services require a transfer at Broadway/W 178 St and take an average of 8h 3m. The schedules shown below are for the next available departures.


7h 45m • 2 changes


7h 35m • 2 changes


8h 19m • 2 changes


7h 52m • 2 changes


7h 45m • 2 changes


7h 35m • 2 changes


8h 19m • 2 changes


7h 52m • 2 changes


7h 45m • 2 changes


7h 35m • 2 changes


8h 19m • 2 changes


7h 52m • 2 changes


7h 45m • 2 changes


7h 35m • 2 changes


8h 19m • 2 changes


7h 52m • 2 changes


7h 45m • 2 changes


7h 30m • 2 changes


8h 15m • 2 changes


7h 53m • 2 changes


7h 48m • 2 changes


7h 45m • 2 changes


8h 20m • 2 changes


7h 49m • 2 changes


7h 47m • 2 changes


7h 45m • 2 changes


8h 20m • 2 changes


7h 49m • 2 changes
Want to know about travelling from Harlem to Hyannis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Harlem to Hyannis. However, there are services departing from Harlem station and arriving at Hyannis station via Boston. The journey, including transfers, takes approximately 8h 3m.
Harlem to Hyannis bus services, operated by MTA Bus Company, depart from New York station.
Harlem to Hyannis bus services, operated by MTA Bus Company, arrive at Hyannis Transportation Center station.
The distance between Harlem and Hyannis is 320.4 km. The road distance is 455 km.
You can take a bus from W 125 St/Saint Nicholas Av to Hyannis Transportation Center via Broadway/W 178 St, New York, Boston, and Boston South Buses in around 8h 19m.