The average bus between Guimarães and Setúbal takes 5h 39m and the fastest bus takes 5h 2m. There is a bus service every few hours from Guimarães to Setúbal. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Guimarães and Setúbal. The earliest departure is at 6:00 AM in the morning, and the last departure from Guimarães is at 8:40 PM which arrives into Setúbal at 2:54 AM. All services require a transfer at Porto and take an average of 5h 39m. The schedules shown below are for the next available departures.


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5h 47m • 2 changesWant to know about travelling from Guimarães to Setúbal? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Guimarães to Setúbal. However, there are services departing from Central de Camionagem de Guimarães station and arriving at Avenida Dom João II station via Porto station and Lisbon station. The journey, including transfers, takes approximately 5h 39m.
Guimarães to Setúbal bus services, operated by FlixBus, depart from Central de Camionagem de Guimarães station.
Guimarães to Setúbal bus services, operated by Carris Metropolitana, arrive at Avenida Dom João II station.
Book your Guimarães to Setúbal bus tickets online with Omio.
The distance between Guimarães and Setúbal is 328.6 km. The road distance is 394 km.
You can take a bus from Central de Camionagem de Guimarães to Avenida Dom João II via Porto, Lisbon, and Gare do Oriente 21-C in around 5h 2m.