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Fort Pierce to Indianapolis buses

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Trip Overview

The average bus between Fort Pierce and Indianapolis takes 35h 3m and the fastest bus takes 31h 38m. The bus runs, on average, 6 times per week from Fort Pierce to Indianapolis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

35h 3m
Duration
1,142 mi
Distance
$223
Average price
6 times a week
Frequency

Fort Pierce to Indianapolis bus times

Buses run 6 times a week between Fort Pierce and Indianapolis. The service departs Fort Pierce at 2:02 PM in the afternoon, which arrives into Indianapolis at 21:40:00. All services require a transfer at Wheeler Ter & Okeechobee Rd and take an average of 35h 3m. The schedules shown below are for the next available departures.

Departing Monday, November 2, 2026

  •  → 

    Arrives next day

    Area Regional Transit St LucieGreyhound USAFlixbus USAFlixbus USA31h 38m • 3 changes

Departing Tuesday, November 3, 2026

  •  → 

    Arrives +2 days

    Area Regional Transit St LucieGreyhound USAFlixbus USAFlixbus USA41h 53m • 3 changes

Departing Wednesday, November 4, 2026

  •  → 

    Arrives +2 days

    Area Regional Transit St LucieGreyhound USAFlixbus USAFlixbus USA41h 53m • 3 changes

Departing Thursday, November 5, 2026

  •  → 

    Arrives next day

    Area Regional Transit St LucieGreyhound USAFlixbus USAFlixbus USA31h 38m • 3 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives next day

    Area Regional Transit St LucieGreyhound USAFlixbus USAFlixbus USA31h 38m • 3 changes

Departing Saturday, November 7, 2026

  •  → 

    Arrives next day

    Area Regional Transit St LucieGreyhound USAFlixbus USAFlixbus USA31h 38m • 3 changes

Frequently asked questions

Want to know about travelling from Fort Pierce to Indianapolis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Fort Pierce to Indianapolis.ExpandLaunch map view
  • Distance: 1,142.5 mi
  • Duration: 35h 3m

What companies run services between Fort Pierce, FL, USA and Indianapolis, IN, USA?

You can take a bus from Orange Ave & N 9th St to Indianapolis via Wheeler Ter & Okeechobee Rd, Fort Pierce, Port St Lucie, and Atlanta Bus Station in around 25h 38m.

Operators