Rome2Rio

Florida to Missouri buses

Find Transport to Missouri

View schedule
QR code to download the Rome2Rio app

Download the Rome2Rio travel app

Scan QR code with your phone to download the app

Download on the App StoreGet it on Google Play

Trip Overview

The average bus between Florida and Missouri takes 28h 43m and the fastest bus takes 28h 29m. The bus service runs several times per day from Florida to Missouri. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

28h 43m
Duration
1,197 mi
Distance
$258
Average price
Twice daily
Frequency

Florida to Missouri bus times

Buses run twice daily between Florida and Missouri. The earliest departure is at 12:08 AM at night, and the last departure from Florida is at 11:37 PM which arrives into Missouri at 3:45 AM. All services require a transfer at JRTC Bay J and take an average of 28h 43m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    Jacksonville TransportFlixbus USAFlixbus USAGreyhound USA28h 54m • 3 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    Jacksonville TransportFlixbus USAGreyhound USAGreyhound USA28h 31m • 3 changes
  •  → 

    Arrives next day

    Jacksonville TransportFlixbus USAFlixbus USAGreyhound USA28h 54m • 3 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    Jacksonville TransportFlixbus USAGreyhound USAGreyhound USA28h 31m • 3 changes
  •  → 

    Arrives next day

    Jacksonville TransportFlixbus USAFlixbus USAGreyhound USA28h 54m • 3 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    Jacksonville TransportFlixbus USAGreyhound USAGreyhound USA28h 31m • 3 changes
  •  → 

    Arrives next day

    Jacksonville TransportFlixbus USAFlixbus USAGreyhound USA28h 29m • 3 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    Jacksonville TransportFlixbus USAGreyhound USAGreyhound USA28h 37m • 3 changes
  •  → 

    Arrives next day

    Jacksonville TransportFlixbus USAFlixbus USAGreyhound USA28h 54m • 3 changes
  •  → 

    Arrives +2 days

    Jacksonville TransportFlixbus USAGreyhound USAGreyhound USA29h 7m • 3 changes

Frequently asked questions

Want to know about travelling from Florida to Missouri? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Florida to Missouri.ExpandLaunch map view
  • Distance: 1,197.1 mi
  • Duration: 28h 43m

What companies run services between Florida, USA and Missouri, USA?

You can take a bus from Newnan St + Ashley St to Kansas City Bus Station via JRTC Bay J, Jacksonville, Atlanta Bus Station, and St Louis Bus Station in around 25h 33m.

Operators