The average bus between Florence and Lecce takes 12h 12m and the fastest bus takes 11h 30m. The bus service runs several times per day from Florence to Lecce. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Florence and Lecce. The earliest departure is at 2:20 AM at night, and the last departure from Florence is at 7:45 PM which arrives into Lecce at 7:50 AM. All services require a transfer, and take on average 12h 12m. The schedules shown below are for the next available departures.

11h 30m • 1 change
Arrives next day

12h 15m • 1 change
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11h 30m • 1 change

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11h 30m • 1 change

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Arrives next day

11h 45m • 1 change

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12h 15m • 1 change

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11h 30m • 1 change
Want to know about travelling from Florence to Lecce? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Florence to Lecce. However, there are services departing from Florence station and arriving at Lecce station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 12h 12m.
Florence to Lecce bus services, operated by FlixBus, depart from Florence Villa Constanza Bus Station.
Florence to Lecce bus services, operated by FlixBus, arrive at Lecce station.
Book your Florence to Lecce bus tickets online with FlixBus.
The distance between Florence and Lecce is 686.6 km. The road distance is 888 km.
You can take a bus from Florence Villa Constanza Bus Station to Lecce via Roma, Autostazione Tiburtina in around 12h 35m.