The average bus between Florence and Differdange takes 16h 35m and the fastest bus takes 16h 30m. There is at least one bus per day from Florence to Differdange. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Florence and Differdange. The earliest departure is at 2:20 PM in the afternoon, and the last departure from Florence is at 4:10 PM which arrives into Differdange at 8:50 AM. All services require a transfer at Milan and take an average of 16h 35m. The schedules shown below are for the next available departures.
Arrives next day



16h 30m • 3 changes
Arrives next day



16h 40m • 3 changes
Arrives next day



16h 30m • 3 changes
Arrives next day



16h 40m • 3 changes
Want to know about travelling from Florence to Differdange? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Florence to Differdange. However, there are services departing from Florence station and arriving at Differdange station via Milano, Autostazione Lampugnano. The journey, including transfers, takes approximately 16h 35m.
Florence to Differdange bus services, operated by FlixBus, depart from Florence Villa Constanza Bus Station.
Florence to Differdange bus services, operated by FlixBus, arrive at Luxembourg, P+R Bouillon station.
Book your Florence to Differdange bus tickets online with FlixBus, VD Luxembourg Transit and Mobiliteit.
The distance between Florence and Differdange is 757.7 km. The road distance is 982 km.
You can take a bus from Florence Villa Constanza Bus Station to Differdange, Opkorn via Milan, Luxembourg, P+R Bouillon, Hollerich, P+R Bouillon, and Gasperich, Stengege Wee in around 16h 16m.